Glomerular and Tubular Epithelial Defects in <i>kd/kd</i> Mice Lead to Progressive Renal Failure
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چکیده
منابع مشابه
Glomerular and tubular epithelial defects in kd/kd mice lead to progressive renal failure.
BACKGROUND/AIM The kd/kd mouse spontaneously develops severe and progressive nephritis leading to renal failure, characterized by cellular infiltration, tubular destruction and glomerular sclerosis. Recent identification of the mutant gene and the observation that podocytes are affected, led to the hypothesis that there are primary renal epithelial cell defects in this strain. METHODS Clinica...
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ژورنال
عنوان ژورنال: American Journal of Nephrology
سال: 2005
ISSN: 0250-8095,1421-9670
DOI: 10.1159/000089709